GSPT1 degrader-12
GSPT1 degrader-12 is a selective molecular glue GSPT1 degrader. GSPT1 degrader-12 exhibits antiproliferative activity against cancer cells in a CRBN- and GSPT1-dependent manner. GSPT1 degrader-12 can be used for leukemia research[1].
Product Specifications
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(CCOC1=CC=CC=C1CCNS(=O)(NC2=CC=C3C(N(CC3=C2)C4CCC(NC4=O)=O)=O)=O)C
Molecular Formula
C26H32N4O6S
Molecular Weight
528.62
References & Citations
[1]Carter TR, et al. SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues. Bioorg Med Chem. 2024 Apr 15;104:117699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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