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GSPT1 degrader-12

GSPT1 degrader-12 is a selective molecular glue GSPT1 degrader. GSPT1 degrader-12 exhibits antiproliferative activity against cancer cells in a CRBN- and GSPT1-dependent manner. GSPT1 degrader-12 can be used for leukemia research[1].

Product Specifications

UNSPSC

12352005

Target

Molecular Glues

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC(CCOC1=CC=CC=C1CCNS(=O)(NC2=CC=C3C(N(CC3=C2)C4CCC(NC4=O)=O)=O)=O)C

Molecular Formula

C26H32N4O6S

Molecular Weight

528.62

References & Citations

[1]Carter TR, et al. SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues. Bioorg Med Chem. 2024 Apr 15;104:117699.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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