MG-Lin3
Lin28 degrader MG-Lin3 is a molecular glucose degrading agent that targets the Lin28 protein. Lin28 degrader MG-Lin3 significantly reduces the Renilla luciferase signal at 100 µM. Lin28 degrader MG-Lin3 inhibits the maturation of tumor microRNA let-7. Lin28 degrader MG-Lin3 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
MicroRNA; Molecular Glues
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Smiles
COC1=CC=C(C=C1)C(/C=C/C(N2CCC(CC2)C(N(C3=CC=CC(C4=NN5C(C)=NN=C5C=C4)=C3)C)=O)=O)=O
Molecular Formula
C30H30N6O4
Molecular Weight
538.60
References & Citations
[1]Kashkush A, et al. PROTAC and Molecular Glue Degraders of the Oncogenic RNA Binding Protein Lin28. Macromol Biosci. 2025 Mar;25 (3) :e2400427.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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