PROTAC BRD9 Degrader-9

PROTAC BRD9 Degrader-9 is an efficient and selective targeting BRD9 PROTAC degrader. PROTAC BRD9 Degrader-9 does not cause significant cytotoxicity. PROTAC BRD9 Degrader-9 can be used for cancer research. (Pink: BRD9 Ligand (HY-107446) ; Blue: CRBN Ligand (HY-W877239) ) [1]

Product Specifications

UNSPSC

12352005

Target

Epigenetic Reader Domain; PROTACs

Related Pathways

Epigenetics; PROTAC

Field of Research

Cancer

Smiles

O=C(NCCOCCOCCNC1=CC=C(OC)C(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)C

Molecular Formula

C41H47N7O11

Molecular Weight

813.85

References & Citations

[1]Bouguenina H, et al. A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity. Chembiochem. 2023 Dec 1;24 (23) :e202300351.