PROTAC BRD9 Degrader-9
PROTAC BRD9 Degrader-9 is an efficient and selective targeting BRD9 PROTAC degrader. PROTAC BRD9 Degrader-9 does not cause significant cytotoxicity. PROTAC BRD9 Degrader-9 can be used for cancer research. (Pink: BRD9 Ligand ; Blue: CRBN Ligand (HY-W877239) )
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Smiles
O=C(NCCOCCOCCNC1=CC=C(OC)C(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)C
Molecular Formula
C41H47N7O11
Molecular Weight
813.85
References & Citations
[1]Bouguenina H, et al. A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity. Chembiochem. 2023 Dec 1;24 (23) :e202300351.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD9
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