UTPU (trisodium)
UTPU trisodium (Compound 19) is a selective P2Y6R agonist with an EC50 of 0.4 μM. UTPU trisodium can activate the intracellular calcium signaling pathway mediated by P2Y6. UTPU trisodium can be used for the research of inflammation[1].
Product Specifications
CAS Number
401618-61-9
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]3O[C@@H](N(C(N4)=O)C=CC4=O)[C@H](O)[C@@H]3O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
Molecular Formula
C18H22N4Na3O20P3
Molecular Weight
776.27
References & Citations
[1]Douglass JG, et al. Lipophilic modifications to dinucleoside polyphosphates and nucleotides that confer antagonist properties at the platelet P2Y12 receptor. J Med Chem. 2008 Feb 28;51 (4) :1007-25.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Isoform
P2Y6 Receptor
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