UTPU (trisodium)

UTPU trisodium (Compound 19) is a selective P2Y6R agonist with an EC50 of 0.4 μM. UTPU trisodium can activate the intracellular calcium signaling pathway mediated by P2Y6. UTPU trisodium can be used for the research of inflammation[1].

Product Specifications

CAS Number

[401618-61-9]

UNSPSC

12352005

Target

P2Y Receptor

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]3O[C@@H](N(C(N4)=O)C=CC4=O)[C@H](O)[C@@H]3O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O

Molecular Formula

C18H22N4Na3O20P3

Molecular Weight

776.27

References & Citations

[1]Douglass JG, et al. Lipophilic modifications to dinucleoside polyphosphates and nucleotides that confer antagonist properties at the platelet P2Y12 receptor. J Med Chem. 2008 Feb 28;51 (4) :1007-25.