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Ciprofloxacin prodrug-1

Ciprofloxacin prodrug-1 is a beta lactase activated prodrug. Ciprofloxacin prodrug-1 has good antibacterial activity against bacteria containing β-lactase (MIC = 63 nM) . Ciprofloxacin prodrug-1 can be used for research on bacterial infections[1].

Product Specifications

CAS Number

[2418537-98-9]

UNSPSC

12352005

Target

Bacterial; Beta-lactamase

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(C(N12)=C(COC(C3=CN(C4CC4)C5=C(C=C(F)C(N6CCNCC6)=C5)C3=O)=O)CS[C@]2([H])[C@H](NC(C)=O)C1=O)O

Molecular Formula

C27H28FN5O7S

Molecular Weight

585.60

References & Citations

[1]Evans LE, et al. Exploitation of Antibiotic Resistance as a Novel Drug Target: Development of a β-Lactamase-Activated Antibacterial Prodrug. J Med Chem. 2019 May 9;62 (9) :4411-4425.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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