RORγt inverse agonist 36
RORγt inverse agonist 36 (S configuration of Compound 16) is a RORγt inverse agonist. RORγt inverse agonist 36 can be used for the research of inflammation and immunology[1].
Product Specifications
CAS Number
[1599530-54-7]
UNSPSC
12352005
Target
ROR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
O[C@@](C1=CN=CN1C)(C2=CC=C(C=C2)Cl)C3=CC4=C(N=C(C(CC5=CC=C(N6C=CC=N6)C=C5)=C4Cl)OC)C=C3
Molecular Formula
C31H25Cl2N5O2
Molecular Weight
570.47
References & Citations
[1]Barbay JK, et al. 6-Substituted quinolines as RORγt inverse agonists. Bioorg Med Chem Lett. 2017 Dec 1;27 (23) :5277-5283.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RORγ
Curated Selection
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