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RORγt inverse agonist 36

RORγt inverse agonist 36 (S configuration of Compound 16) is a RORγt inverse agonist. RORγt inverse agonist 36 can be used for the research of inflammation and immunology[1].

Product Specifications

CAS Number

1599530-54-7

UNSPSC

12352005

Target

ROR

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology

Smiles

O[C@@](C1=CN=CN1C)(C2=CC=C(C=C2)Cl)C3=CC4=C(N=C(C(CC5=CC=C(N6C=CC=N6)C=C5)=C4Cl)OC)C=C3

Molecular Formula

C31H25Cl2N5O2

Molecular Weight

570.47

References & Citations

[1]Barbay JK, et al. 6-Substituted quinolines as RORγt inverse agonists. Bioorg Med Chem Lett. 2017 Dec 1;27 (23) :5277-5283.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RORγ

Frequently Asked Questions

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