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ACSL5-IN-2

ACSL5-IN-2 (Compound B) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-2 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-2 can inhibit cancer cells growth. ACSL5-IN-2 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis[1].

Product Specifications

CAS Number

[3098297-74-3]

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease

Purity

98.78

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC[C@@H](OC1=C(F)C(F)=C(C(NS(C2=CC=C(OCCN(C)C)C=C2)(=O)=O)=O)C=C1)C3=CC=C(OCC4CC4)C=N3

Molecular Formula

C29H33F2N3O6S

Molecular Weight

589.65

References & Citations

[1]Thomas Bernard LEVY, et al. Compounds and methods of their use. WO2025174957A1. 2025-02-13

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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