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ACSL5-IN-1

ACSL5-IN-1 (Compound A) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-1 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-1 can inhibit cancer cells growth. ACSL5-IN-1 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis[1].

Product Specifications

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer; Metabolic Disease

Smiles

O=C(NS(=O)(C(C)(C)C)=O)C1=CC=C(O[C@@H](C2=NC=C(OC3=CC=CN=C3)C=C2)C)C(C(F)(F)F)=C1

Molecular Formula

C24H24F3N3O5S

Molecular Weight

523.52

References & Citations

[1]Thomas Bernard LEVY, et al. Compounds and methods of their use. WO2025174957A1. 2025-02-13

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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