3-[4- (2-Propyn-1-yloxy) phenyl]-2H-azirine

3-[4- (2-Propyn-1-yloxy) phenyl]-2H-azirine (Compound AZ-9) is a reactive probe based on 3-phenyl-2H-azirine, enabling chemoselective bioconjugation of carboxyl residues in proteins with excellent labeling efficiency and specificity under both in vitro and in situ conditions in live cells[1].

Product Specifications

CAS Number

[2422137-06-0]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Smiles

C#CCOC1=CC=C(C2=NC2)C=C1

Molecular Formula

C11H9NO

Molecular Weight

171.20

References & Citations

[1]Ma N, et al. 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142 (13) :6051-6059.