GSTO1-IN-5

GSTO1-IN-5 is a potent and selective glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50of 0.22 nM. GSTO1-IN-5 can be used for the researches of cancer and inflammation, such as colon cancer[1].

Product Specifications

CAS Number

[2290641-22-2]

UNSPSC

12352005

Target

Glutathione S-transferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

CC1=NOC(CN(C(C=C)=O)C2=NC(C3=C(C=CC=C3)O)=CS2)=C1

Molecular Formula

C17H15N3O3S

Molecular Weight

341.38

References & Citations

[1]Dai W, et al. Structure-Based Design of N- (5-Phenylthiazol-2-yl) acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors. J Med Chem. 2019 Mar 28;62 (6) :3068-3087.