N- (Azido-PEG4) -N- (PEG4-Val-Cit-PAB-MMAF) -N- (PEG4-Val-Cit-PAB-Exatecan)
N- (Azido-PEG4) -N- (PEG4-Val-Cit-PAB-MMAF) -N- (PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N- (Azido-PEG4) -N- (PEG4-Val-Cit-PAB-MMAF) -N- (PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
O=C(N[C@@H](C(C)C)C(N[C@H](C(NC1=CC=C(COC(N(C)[C@H](C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@H]([C@H](OC)[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)CCC2)=O)C)=O)=O)C(C)C)=O)C=C1)=O)CCCNC(N)=O)=O)CCOCCOCCOCCOCCC(N(CCOCCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C4)=CC=C4COC(N[C@H]5CCC6=C7C5=C8C(C(N9C8)=CC([C@](CC)(O)C(OC%10)=O)=C%10C9=O)=NC7=CC(F)=C6C)=O)=O)=O)=O)=O
Molecular Formula
C134H199FN22O37
Molecular Weight
2729.14
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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