N- (TCO-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan)
N- (TCO-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N- (TCO-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
CN([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)CCC1)=O)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@@H](NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCC(N(CCOCCOCCOCCOCCNC(OC4CCC/C=C/CC4)=O)CCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C5)=CC=C5COC(N[C@H]6CCC7=C8C6=C9C(C(N%10C9)=CC([C@](CC)(O)C(OC%11)=O)=C%11C%10=O)=NC8=CC(F)=C7C)=O)=O)=O)=O)=O)=O)=O)CCCNC(N)=O)=O)=O)=O)=O
Molecular Formula
C143H215FN20O38
Molecular Weight
2841.35
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740178-500 1x 500 µL
CD50 (ICAM-3) (186-2G9), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880149-100 1x 100 µL
CD106 / VCAM1 (1.4C3), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400281-500 1x 500 µL
Insulin (E2-E3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470965-500 1x 500 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details