N- (Amino-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan)

N- (Amino-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N- (Amino-PEG4) -N- (PEG4-Val-Cit-PAB-MMAE) -N- (PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

Product Specifications

UNSPSC

12352211

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin; Topoisomerase

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

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