Zodasiran (sodium)

Zodasiran sodium is a siRNA targeted to ANGPTL3 in the liver.

Product Specifications

CAS Number

[2232918-74-8]

Product Name Alternative

ARO-ANG3 sodium

UNSPSC

12352208

Target

ANGPTL

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

[Zodasiran(sodium)]

Molecular Formula

C491H603F13N162Na43O309P43S7

Molecular Weight

16509.90

References & Citations

[1]Rosenson RS, Gaudet D, Hegele RA, et al. Zodasiran, an RNAi Therapeutic targeted to ANGPTL3, for Mixed Hyperlipidemia. N Engl J Med. 2024;391 (10) :913-925.|[2]Kamrul-Hasan ABM, Dutta D, Nagendra L, Mondal S, Bhattacharya S, Kalra S. Safety and Efficacy of the Novel RNA Interference Therapies for Hypertriglyceridemia and Mixed Hyperlipidemia Management: A Systematic Review and Meta-analysis. Endocr Pract. 2024;30 (11) :1103-1112.