Zintevir (sodium)

Zintevir sodium is an antisense oligonucleotide that targets HIV-1 integrase.

Product Specifications

Product Name Alternative

AR177 sodium; T30177 sodium

UNSPSC

12352208

Target

HIV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

[Zintevir(sodium)]

References & Citations

[1]Ojwang JO, Buckheit RW, Pommier Y, et al. T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1995;39 (11) :2426-2435.|[2]Mukundan VT, Do NQ, Phan AT. HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges. Nucleic Acids Res. 2011;39 (20) :8984-8991.