Umedaptanib pegol (sodium)

Umedaptanib pegol sodium is an anti-fibroblast growth factor-2 (FGF2) aptamer. It is used for the study of neovascular age-related macular degeneration (nAMD) .

Product Specifications

Product Name Alternative

RBM-007 sodium

UNSPSC

12352208

Target

FGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Others

Smiles

[Umedaptanibpegol(sodium)]

References & Citations

[1]Pereira DS, Akita K, Bhisitkul RB, et al. Safety and tolerability of intravitreal umedaptanib pegol (anti-FGF2) for neovascular age-related macular degeneration (nAMD) : a phase 1, open-label study. Eye (Lond) . 2024;38 (6) :1149-1154.|[2]Matsuda Y, Nonaka Y, Futakawa S, et al. Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease. Mol Ther Nucleic Acids. 2019;17:819-828.|[3]Kimura T, Bosakova M, Nonaka Y, et al. An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice. Sci Transl Med. 2021;13 (592) :eaba4226.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 2