Umedaptanib pegol
Umedaptanib pegol is an anti-fibroblast growth factor-2 (FGF2) aptamer. It is used for the study of neovascular age-related macular degeneration (nAMD) .
Product Specifications
CAS Number
2734771-59-4
Product Name Alternative
RBM-007
UNSPSC
12352208
Target
FGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Smiles
[Umedaptanibpegol]
References & Citations
[1]Pereira DS, Akita K, Bhisitkul RB, et al. Safety and tolerability of intravitreal umedaptanib pegol (anti-FGF2) for neovascular age-related macular degeneration (nAMD) : a phase 1, open-label study. Eye (Lond) . 2024;38 (6) :1149-1154.|[2]Matsuda Y, Nonaka Y, Futakawa S, et al. Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease. Mol Ther Nucleic Acids. 2019;17:819-828.|[3]Kimura T, Bosakova M, Nonaka Y, et al. An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice. Sci Transl Med. 2021;13 (592) :eaba4226.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
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