Solbinsiran
Solbinsiran is a siRNA targeted to hepatic ANGPTL3.
Product Specifications
CAS Number
2718150-11-7
Product Name Alternative
LY3561774
UNSPSC
12352208
Target
ANGPTL
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
[Solbinsiran]
Molecular Formula
C653H859O412N229F11P57S6
Molecular Weight
20674.90
References & Citations
[1]Ray KK, Oru E, Rosenson RS, et al. Durability and efficacy of solbinsiran, a GalNAc-conjugated siRNA targeted to ANGPTL3, in adults with mixed dyslipidaemia (PROLONG-ANG3) : a double-blind, randomised, placebo-controlled, phase 2 trial. Lancet. 2025;405 (10489) :1594-1607.|[2]Ray KK, Linnebjerg H, Michael LF, et al. Effect of ANGPTL3 Inhibition With Solbinsiran in Preclinical and Early Human Studies. J Am Coll Cardiol. 2025;85 (19) :1803-1818.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Frequently Asked Questions
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