Renadirsen (sodium)

Renadirsen sodium is an antisense oligonucleotide that induces robust Exon 45 skipping for Dystrophin in vivo.

Product Specifications

Product Name Alternative

DS-5141b sodium

UNSPSC

12352208

Target

Dystrophin

Related Pathways

Cytoskeleton

Field of Research

Others

Smiles

[Renadirsen(sodium)]

References & Citations

[1]Ito K, Takakusa H, Kakuta M, et al. Renadirsen, a Novel 2'OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo. Curr Issues Mol Biol. 2021;43 (3) :1267-1281.|[2]Yamamura N, Takakusa H, Asano D, et al. Tissue distribution of renadirsen sodium, a dystrophin exon-skipping antisense oligonucleotide, in heart and diaphragm after subcutaneous administration to cynomolgus monkeys. Nucleosides Nucleotides Nucleic Acids. 2025;44 (8) :626-642.