Pixofisiran
Pixofisiran is a siRNA in STP705. It targets to TGF‐β1. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
Product Specifications
CAS Number
1152798-48-5
UNSPSC
12352208
Target
TGF-β Receptor
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
[Pixofisiran]
References & Citations
[1]Nestor MS, Hetzel J, Awad N, Bhupalam V, Lu P, Molyneaux M. A Novel Injectable Polypeptide Nanoparticle Encapsulated siRNA Targeting TGF-β1 and COX-2 for Localized Fat Reduction II: Phase I Clinical Trial. J Cosmet Dermatol. 2025;24 (2) :e16722.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Frequently Asked Questions
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