Pegpleranib
Pegpleranib is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.
Product Specifications
CAS Number
[1618657-13-8]
Product Name Alternative
Fovista
UNSPSC
12352208
Target
PDGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
[Pegpleranib]
References & Citations
[1]Hussain RM, Ciulla TA. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration. Expert Opin Emerg Drugs. 2017;22 (3) :235-246.|[2]Schlottmann PG, Alezzandrini AA, Zas M, Rodriguez FJ, Luna JD, Wu L. New Treatment Modalities for Neovascular Age-Related Macular Degeneration. Asia Pac J Ophthalmol (Phila) . 2017;6 (6) :514-519.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
039038-HRP 200 µL
NNOS, phosphorylated (S1417) (NOS1, Nitric oxide synthase, brain, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, Peptidyl-cysteine S-nitrosylase NOS1, bNOS) (Azide free) (HRP) discontinued
Ask
View Details 
GTR15095707 1 Vial
Lentiviral human VAX2 shRNA (UAS) - Lentiviral human VAX2 shRNA (UAS) plasmid
Ask
View Details 131816-ML750 100 µL
PRKG1 (cGMP-dependent Protein Kinase 1, cGK 1, cGK1, cGMP-dependent Protein Kinase I, cGKI, PRKG1B, PRKGR1A, PRKGR1B, DKFZp686K042, FLJ36117, MGC71944) (MaxLight 750) discontinued
Ask
View Details