Lufepirsen
Lufepirsen is an unmodified antisense oligonucleotide targeted to Connexin43 (Cx43) . Connexin43 is a specific protein in the eye, which plays a role in wound healing.
Product Specifications
CAS Number
[287122-58-1]
UNSPSC
12352208
Target
Connexin
Related Pathways
Cytoskeleton
Field of Research
Others
Smiles
[Lufepirsen]
References & Citations
[1]Antisense compounds targeted to connexins and methods of use thereof. WO2005053600A2|[2]Shawn Scranton; Joshua H. Hou; Dharamveer Singh Choudhary; Colin R. Green; Maria Feldman; Dipak Panigrahi.A Phase 2, randomized, prospective, double-masked, vehicle-controlled study to assess the safety and efficacy of topical NEXAGON® in subjects with persistent corneal epithelial defects (PCED) resulting from severe ocular chemical and/or thermal injuries.Investigative Ophthalmology & Visual Science June 2023, Vol.64, 3119.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
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