GNKG168 (sodium)
GNKG168 sodium is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.
Product Specifications
UNSPSC
12352208
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
[GNKG168(sodium)]
References & Citations
[1]Ronsley R, Kariminia A, Ng B, et al. The TLR9 agonist (GNKG168) induces a unique immune activation pattern in vivo in children with minimal residual disease positive acute leukemia: Results of the TACL T2009-008 phase I study. Pediatr Hematol Oncol. 2019;36 (8) :468-481.|[2]Muthusamy N, Breidenbach H, Andritsos L, et al. Enhanced detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide in combination with pokeweed mitogen and phorbol myristate acetate. Cancer Genet. 2011;204 (2) :77-83.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 1
Curated Selection
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