GNKG168

GNKG168 is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.

Product Specifications

CAS Number

[2243120-19-4]

UNSPSC

12352208

Target

Toll-like Receptor (TLR)

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

[GNKG168]

References & Citations

[1]Ronsley R, Kariminia A, Ng B, et al. The TLR9 agonist (GNKG168) induces a unique immune activation pattern in vivo in children with minimal residual disease positive acute leukemia: Results of the TACL T2009-008 phase I study. Pediatr Hematol Oncol. 2019;36 (8) :468-481.|[2]Muthusamy N, Breidenbach H, Andritsos L, et al. Enhanced detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide in combination with pokeweed mitogen and phorbol myristate acetate. Cancer Genet. 2011;204 (2) :77-83.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 1