Gataparsen (sodium)

Gataparsen sodium is an antisense oligonucleotide directed against survivin mRNA with potential antitumor activity.

Product Specifications

Product Name Alternative

LY 2181308 (sodium)

UNSPSC

12352208

Target

Survivin

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

[Gataparsen(sodium)]

References & Citations

[1]Wiechno P, Somer BG, Mellado B, et al. A randomised phase 2 study combining LY2181308 sodium (survivin antisense oligonucleotide) with first-line docetaxel/prednisone in patients with castration-resistant prostate cancer. Eur Urol. 2014;65 (3) :516-520.|[2]Tanioka M, Nokihara H, Yamamoto N, et al. Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011;68 (2) :505-511.