Gataparsen

Gataparsen is an antisense oligonucleotide directed against survivin mRNA with potential antitumor activity.

Product Specifications

CAS Number

[1065019-70-6]

Product Name Alternative

LY 2181308

UNSPSC

12352208

Target

Survivin

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

[Gataparsen]

References & Citations

[1]Wiechno P, Somer BG, Mellado B, et al. A randomised phase 2 study combining LY2181308 sodium (survivin antisense oligonucleotide) with first-line docetaxel/prednisone in patients with castration-resistant prostate cancer. Eur Urol. 2014;65 (3) :516-520.|[2]Tanioka M, Nokihara H, Yamamoto N, et al. Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011;68 (2) :505-511.