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Bazlitoran

Bazlitoran, an oligonucleotide, is an antagonist of TLR7, TLR8, and TLR9.

Product Specifications

CAS Number

1378549-07-5

Product Name Alternative

IMO-8400

UNSPSC

12352208

Target

Toll-like Receptor (TLR)

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

[Bazlitoran]

Molecular Formula

C179H233N52O101P17S17

Molecular Weight

5800.70

References & Citations

[1]Kim YJ, Schiopu E, Dankó K, et al. A phase 2, double-blinded, placebo-controlled trial of toll-like receptor 7/8/9 antagonist, IMO-8400, in dermatomyositis. J Am Acad Dermatol. 2021;84 (4) :1160-1162.|[2]Balak DM, van Doorn MB, Arbeit RD, et al. IMO-8400, a toll-like receptor 7, 8, and 9 antagonist, demonstrates clinical activity in a phase 2a, randomized, placebo-controlled trial in patients with moderate-to-severe plaque psoriasis. Clin Immunol. 2017;174:63-72.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 2

Frequently Asked Questions

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