Bazlitoran
Bazlitoran, an oligonucleotide, is an antagonist of TLR7, TLR8, and TLR9.
Product Specifications
CAS Number
[1378549-07-5]
Product Name Alternative
IMO-8400
UNSPSC
12352208
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
[Bazlitoran]
Molecular Formula
C179H233N52O101P17S17
Molecular Weight
5800.70
References & Citations
[1]Kim YJ, Schiopu E, Dankó K, et al. A phase 2, double-blinded, placebo-controlled trial of toll-like receptor 7/8/9 antagonist, IMO-8400, in dermatomyositis. J Am Acad Dermatol. 2021;84 (4) :1160-1162.|[2]Balak DM, van Doorn MB, Arbeit RD, et al. IMO-8400, a toll-like receptor 7, 8, and 9 antagonist, demonstrates clinical activity in a phase 2a, randomized, placebo-controlled trial in patients with moderate-to-severe plaque psoriasis. Clin Immunol. 2017;174:63-72.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Curated Selection
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