ALN-3133 (sodium)
ALN-3133 sodium is a siRNA that targets VEGF, and it is one of the siRNAs in ALN-VSP.ALN-VSP is a lipid nanoparticle formulation containing two siRNAs for kinesin spindle protein (KSP) and VEGF with potential antitumor activity.
Product Specifications
Product Name Alternative
AD3133 (sodium)
UNSPSC
12352208
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
[ALN-3133(sodium)]
References & Citations
[1]COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 GENE. US20110015250A1|[2]Tabernero J, Shapiro GI, LoRusso PM, et al. First-in-humans trial of an RNA interference therapeutic targeted to VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 2013;3 (4) :406-417.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 1
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