ALN-12115
ALN-12115 is a siRNA that targets kinesin spindle protein (KSP), and it is one of the siRNAs in ALN-VSP.ALN-VSP is a lipid nanoparticle formulation containing two siRNAs for KSP and VEGF with potential antitumor activity.
Product Specifications
CAS Number
3031494-36-4
Product Name Alternative
AD12115
UNSPSC
12352208
Target
Kinesin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[ALN-12115]
References & Citations
[1]COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 GENE. US20110015250A1|[2]Tabernero J, Shapiro GI, LoRusso PM, et al. First-in-humans trial of an RNA interference therapeutic targeted to VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 2013;3 (4) :406-417.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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