AGN-745 (sodium)

AGN-745 sodium is a chemically modified siRNA targeted to VEGFR-1. It is used for the study of Macular degeneration.

Product Specifications

Product Name Alternative

AGN-211745 (sodium) ; Sirna-027 (sodium)

UNSPSC

12352208

Target

VEGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Others

Smiles

[AGN-745(sodium)]

References & Citations

[1]Jiang J, Zhang X, Tang Y, Li S, Chen J. Progress on ocular siRNA gene-silencing therapy and drug delivery systems. Fundam Clin Pharmacol. 2021;35 (1) :4-24.|[2]Shen J, Samul R, Silva RL, et al. Suppression of ocular neovascularization with siRNA targeted to VEGF receptor 1. Gene Ther. 2006;13 (3) :225-234.