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14-3-3-IN-2

14-3-3-IN-2 is a 14-3-3 protein inhibitor with an IC50 of 15 nM. 14-3-3-IN-2 can disrupt the interaction of 14-3-3α with aminopeptidase N and down-regulate 14-3-3α increased MMP-1 mRNA levels[1].

Product Specifications

CAS Number

919751-10-3

UNSPSC

12352005

Target

MMP

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Purity

98.41

Smiles

O=C(COC1=C(P(O)(O)=O)C=CC=C1)NC2CCCCC2

Molecular Formula

C14H20NO5P

Molecular Weight

313.29

References & Citations

[1]Thiel P, et al. Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem Commun (Camb) . 2013 Oct 4;49 (76) :8468-70.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MMP-1

Available Sizes

Frequently Asked Questions

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