14-3-3-IN-2
14-3-3-IN-2 is a 14-3-3 protein inhibitor with an IC50 of 15 nM. 14-3-3-IN-2 can disrupt the interaction of 14-3-3α with aminopeptidase N and down-regulate 14-3-3α increased MMP-1 mRNA levels[1].
Product Specifications
CAS Number
[919751-10-3]
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
98.41
Smiles
O=C(COC1=C(P(O)(O)=O)C=CC=C1)NC2CCCCC2
Molecular Formula
C14H20NO5P
Molecular Weight
313.29
References & Citations
[1]Thiel P, et al. Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem Commun (Camb) . 2013 Oct 4;49 (76) :8468-70.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-177590/14-3-3-IN-2-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-1
Available Sizes
Curated Selection
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