N1-Methyl-GTP
N1-Methyl-GTP is a nucleotide analog of GTP. N1-Methyl-GTP shows a half-maximal inhibitory concentration of 8.1 μM and an inhibition constant of 1.5 μM against yeast RTPase. N1-Methyl-GTP can be used as a probe molecule to explore the structural flexibility of the active site of RNA triphosphatase and the mechanism of substrate recognition[1].
Product Specifications
CAS Number
[52940-67-7]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Others
Smiles
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3)=C2N=C(N)N1C
Molecular Formula
C11H18N5O14P3
Molecular Weight
537.21
References & Citations
[1]Issur M, et al. Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase. Nucleic Acids Res. 2009 Jun;37 (11) :3714-22.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Curated Selection
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