GP1 precursor

GP1 precursor has high affinity to GPIIb/IIIa receptors of activated platelets. GP1 precursor can be radiolabeled with [18F] and used as a PET Tracer for visualizing active platelet aggregation at the molecular level. GP1 precursor can be used for the detection of Thrombi[1].

Product Specifications

CAS Number

[1423134-36-4]

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cardiovascular Disease

Smiles

O=C([C@H]1CN(CCC1)C(CCC2CCN(CC2)C(OC(C)(C)C)=O)=O)N[C@H](C3=CN=CC(OCCOS(=O)(C4=CC=C(C=C4)C)=O)=C3)CC(OC(C)(C)C)=O

Molecular Formula

C40H58N4O10S

Molecular Weight

786.97

References & Citations

[1]Hugenberg V, et al. GMP-Compliant Radiosynthesis of [18F]GP1, a Novel PET Tracer for the Detection of Thrombi. Pharmaceuticals (Basel) . 2021 Jul 28;14 (8) :739.