Cholesteryl γ-aminobutyrate
Cholesteryl γ-aminobutyrate is a γ-aminobutyric acid (GABA) -mimetic prodrug. Cholesteryl γ-aminobutyrate inhibits the orthodromically-evoked discharge of pyramidal cells in the CA1 region of the hippocampus. Cholesteryl γ-aminobutyrate suppresses the open-field activity of mice and rats in a dose-dependent manner and inhibits Bicuculline -induced seizures in mice. Cholesteryl γ-aminobutyrate can be used for the study of CNS diseases related to impaired GABAergic neuronal function[1].
Product Specifications
CAS Number
89210-68-4
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(CCCN)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
Molecular Formula
C31H53NO2
Molecular Weight
471.76
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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