Delpacibart etedesiran
Delpacibart braxlosiran (Del-desiran), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) that binds to the transferrin receptor 1 (TfR1) conjugated with a siRNA targeting DMPK (DM1 protein kinase) mRNA. Delpacibart braxlosiran is used for the study of myotonic dystrophy type 1 (DM1).
Product Specifications
CAS Number
2653183-68-5
Product Name Alternative
Del-desiran; AOC 1001
UNSPSC
12352005
Target
Antibody-Oligonucleotide Conjugates (AOCs) ; Transferrin Receptor
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
[Delpacibartetedesiran]
References & Citations
[1]Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use. WO2025177244A1|[2]WHO Drug Information - Volume 37, No. 1, 2023
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
Phase 3
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