Delpacibart zotadirsen
Delpacibart zotadirsen (Del-zota), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated to a phosphorodiamidate morpholino conjugate (PMO), Delpacibart zotadirsen is designed to deliver phosphorodiamidate morpholino oligomers (PMOs) to skeletal muscle and heart tissue to specifically skip exon 44 of the dystrophin gene and enable production of near-full length dystrophin. Delpacibart zotadirsen is used for the study of myotonic dystrophy type 1 (DM1) [1].
Product Specifications
CAS Number
[2929240-20-8]
Product Name Alternative
Del-zota; AOC 1044
UNSPSC
12352005
Target
Antibody-Oligonucleotide Conjugates (AOCs) ; Transferrin Receptor
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease
Smiles
[Delpacibartzotadirsen]
References & Citations
[1]Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use. WO2025177244A1
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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