AV5116
AV5116 is a cap-dependent endonuclease inhibitor (CENI) that binds to the active site of the cap-dependent endonuclease (CEN) located in the N-terminal domain of the polymerase acidic. AV5116 exhibits potent inhibitory activity against influenza viruses (influenza A, B, and C viruses) . AV5116 can be used for the study of influenza virus infections[1].
Product Specifications
CAS Number
2417851-90-0
UNSPSC
12352005
Target
Endonuclease; Influenza Virus
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
99.57
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C(N(C=C2)N([C@]3([H])C4=C(SCC5=C(F)C(F)=CC=C53)C=CS4)[C@@]6([H])N1CCOC6)=C(O)C2=O
Molecular Formula
C22H17F2N3O4S2
Molecular Weight
489.51
References & Citations
[1]Chesnokov A, et al. Influenza C virus susceptibility to antivirals with different mechanisms of action. Antimicrob Agents Chemother. 2024 May 2;68 (5) :e0172723.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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