Fmoc-PEG6-VCP-Eribulin
Fmoc-PEG6-VCP-Eribulin is the derivative of Eribulin. Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules[1].
Product Specifications
CAS Number
2841688-52-4
UNSPSC
12352005
Target
ADC Payload; Apoptosis; Drug Derivative; Microtubule/Tubulin
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Cancer
Smiles
O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)NCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C4)=CC=C4COC(NC[C@@H](O)C[C@@H]5[C@H](OC)[C@](CC(C[C@]6([H])O[C@]7([H])[C@]8([H])O[C@@]9(O[C@@]%10([H])[C@@](O[C@]8([H])[C@@]%10([H])O[C@@]7([H])CC6)([H])C9)CC%11)=O)([H])[C@](O5)([H])C[C@@](C([C@H](C)C%12)=C)([H])O[C@@]%12([H])CC[C@@]%13([H])C(C[C@@]%11([H])O%13)=C)=O)=O)=O)=O
Molecular Formula
C89H125N7O25
Molecular Weight
1692.98
References & Citations
[1]Huang Jinkun, et al. Preparation method for dual-drug-linker of adc and use thereof. WO2022199429A1. 2022-09-29.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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