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Fmoc-Val-Cit-PAB-Exatecan

Fmoc-Val-Cit-PAB-Exatecan is a Drug-linker conjugate for ADC. Fmoc-Val-Cit-PAB-Exatecan contains the ADC linker (Fmoc-Val-Cit-PAB) and a DNA topoisomerase I inhibitor Exatecan.

Product Specifications

CAS Number

2754384-69-3

UNSPSC

12352005

Target

Drug Derivative; Drug-Linker Conjugates for ADC; Topoisomerase

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

FC(C=C(N=C1C2=CC3=C4COC([C@](CC)3O)=O)C5=C6CC[C@H](NC(OCC7=CC=C(NC([C@@H](NC([C@@H](NC(OCC8C9=CC=CC=C9C%10=CC=CC=C%108)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C7)=O)C5=C1CN2C4=O)=C6C

Molecular Formula

C58H59FN8O11

Molecular Weight

1063.13

References & Citations

[1]Xiao Shang, et al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2. 2023-12-01.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Topo I

Frequently Asked Questions

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