MGL-IN-2

MGL-IN-2 (Compound 1) is a MGL inhibitor with IC50 values of 0.006 μM and 0.0121 μM for mutant MGL and wild-type MGL, respectively. MGL-IN-2 can be used in the research of metabolic diseases[1].

Product Specifications

CAS Number

[1252773-92-4]

UNSPSC

12352005

Target

MAGL

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

O=C(C1=CSC=N1)N2CCN(C3CN(C(C4=C(Cl)C5=CC=C(C(F)(F)F)C=C5S4)=O)C3)CC2

Molecular Formula

C21H18ClF3N4O2S2

Molecular Weight

514.97

References & Citations

[1]Margery CONNELLY, et al. Monoacylglycerol lipase inhibitors for the treatment of metabolic diseases and related disorders. WO2013049293A1. WIPO (PCT) . 2012-09-27.