MGL-IN-2
MGL-IN-2 (Compound 1) is a MGL inhibitor with IC50 values of 0.006 μM and 0.0121 μM for mutant MGL and wild-type MGL, respectively. MGL-IN-2 can be used in the research of metabolic diseases[1].
Product Specifications
CAS Number
1252773-92-4
UNSPSC
12352005
Target
MAGL
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C(C1=CSC=N1)N2CCN(C3CN(C(C4=C(Cl)C5=CC=C(C(F)(F)F)C=C5S4)=O)C3)CC2
Molecular Formula
C21H18ClF3N4O2S2
Molecular Weight
514.97
References & Citations
[1]Margery CONNELLY, et al. Monoacylglycerol lipase inhibitors for the treatment of metabolic diseases and related disorders. WO2013049293A1. WIPO (PCT) . 2012-09-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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