NHS-cBu-Cit-PAB
NHS-cBu-Cit-PAB is an intermediate of ADC linker. NHS-cBu-Cit-PAB can be used for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1799660-11-9]
UNSPSC
12352005
Target
ADC Linker; Drug Intermediate
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Field of Research
Others
Smiles
O=C(C1(C(N[C@H](C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O)=O)CCC1)ON3C(CCC3=O)=O
Molecular Formula
C23H29N5O8
Molecular Weight
503.51
References & Citations
[1]Wei B, et al. Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. J Med Chem. 2018 Feb 8;61 (3) :989-1000.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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