P0064
P0064 is a selective inhibitor targeting the PR domain of PRDM16. P0064 selectively reduces proliferation and survival of FLT3-ITD+ leukemia cells. P0064 is promising for research of acute myeloid leukemia (AML) [1].
Product Specifications
CAS Number
299443-19-9
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(C1=C(O)C=CC=C1)N/N=C(C2=C(N3)C=CC([N+]([O-])=O)=C2)\C3=O
Molecular Formula
C15H10N4O5
Molecular Weight
326.26
References & Citations
[1]Zhai F, et al. PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia Progression. Cancer Res. 2025 Feb 1;85 (3) :535-550.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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