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T26A

T26A is a competitive prostaglandin transporter (PGT) inhibitor (Ki=378 nM) . T26A is promising for research of prostaglandin signaling and inflammatory diseases (e.g., glaucoma, pulmonary hypertension) [1].

Product Specifications

CAS Number

[958860-12-3]

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Smiles

O=C(NCCOCCOCCN=[N+]=[N-])C1=CC=C(NC2=NC(NCCOCCOCCNC(C3=CC=CC=C3)=O)=NC(NC4=CC=C(O)C=C4)=N2)C=C1

Molecular Formula

C35H43N11O7

Molecular Weight

729.79

References & Citations

[1]Chi Y, et al. Development of a high-affinity inhibitor of the prostaglandin transporter. J Pharmacol Exp Ther. 2011 Nov;339 (2) :633-41.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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