(+) -PM 92131

(+) -PM 92131 is the active enantiomer of (±) -PM 92131 (HY-177437) . (+) -PM 92131 is a non-nucleoside HIV-1 inhibitor. (+) -PM 92131 has an anti-HIV-1 activity with EC50s of 0.8 and 0.6 μM for HIV-1 RF strain in XTT cytoprotection and syncytium-forming assay, respectively. (+) -PM 92131 can be used for HIV infections research[1].

Product Specifications

CAS Number

[167937-11-3]

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[C@@]12[C@@]3(C(C)(CCC2)C)[C@](C([C@H]1C4=COC=C4)=O)([H])O3

Molecular Formula

C16H20O3

Molecular Weight

260.33

References & Citations

[1]Jesús A, et al. A novel non nucleoside compound with high in vitro anti-HIV-1 activity. Absolute stereochemistry determination[J]. Bioorganic & Medicinal Chemistry Letters, 1995, 5 (14) : 1471-1474.