AM11542
AM11542 is a orthosteric agonist of cannabinoid receptor 1 (CB1), with a reported binding affinity (Ki) of 0.11 nM. AM11542 can be used for the study of CB1 receptor activation and related allosteric modulation mechanisms[1].
Product Specifications
CAS Number
152674-95-8
UNSPSC
12352005
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OC1=C2[C@@]3([H])[C@](CC=C(C3)C)([H])C(C)(OC2=CC(C(C)(C)CCCCCCBr)=C1)C
Molecular Formula
C25H37BrO2
Molecular Weight
449.46
References & Citations
[1]Aderibigbe AO, et al. Negative allosteric modulators of cannabinoid receptor 1: Ternary complexes including CB1, orthosteric CP55940 and allosteric ORG27569. J Biomol Struct Dyn. 2022 Aug;40 (13) :5729-5747.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1
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