PDD00031704
PDD00031704 is a poly (ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of >60 µM[1].
Product Specifications
CAS Number
[2032096-42-5]
UNSPSC
12352005
Target
Poly (ADP-ribose) Glycohydrolase (PARG)
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Smiles
O=C1C2=CC(S(=O)(N(C3(CC3)C)C)=O)=CC=C2N(CC4=CC(C)=NN4C)C(N1CC5=CN=C(C)S5)=O
Molecular Formula
C24H28N6O4S2
Molecular Weight
528.65
References & Citations
[1]James DI, et al. First-in-Class Chemical Probes against Poly (ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib. ACS Chem Biol. 2016 Nov 18;11 (11) :3179-3190.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-177420/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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