MU1787
MU1787 (Compound 22h) is a Homeodomain interacting protein kinase (HIPK) inhibitor with IC50s of 285, 123 and 283 nM for HIPK1, HIPK2 and HIPK3, respectively. HIPK have distinct or contradictory effects on cell proliferation and tissue growth[1].
Product Specifications
CAS Number
2624098-97-9
UNSPSC
12352005
Target
DYRK
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Smiles
CC(C)(C)C1=CC=C(C=C1)C2=COC(C=C3)=C2N=C3C4=CN=NN4
Molecular Formula
C19H18N4O
Molecular Weight
318.37
References & Citations
[1]Němec V, et al. Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core. Eur J Med Chem. 2021 Apr 5;215:113299.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIPK
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