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MU1787

MU1787 (Compound 22h) is a Homeodomain interacting protein kinase (HIPK) inhibitor with IC50s of 285, 123 and 283 nM for HIPK1, HIPK2 and HIPK3, respectively. HIPK have distinct or contradictory effects on cell proliferation and tissue growth[1].

Product Specifications

CAS Number

2624098-97-9

UNSPSC

12352005

Target

DYRK

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Others

Smiles

CC(C)(C)C1=CC=C(C=C1)C2=COC(C=C3)=C2N=C3C4=CN=NN4

Molecular Formula

C19H18N4O

Molecular Weight

318.37

References & Citations

[1]Němec V, et al. Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core. Eur J Med Chem. 2021 Apr 5;215:113299.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIPK

Frequently Asked Questions

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