JSD26
JSD26 is a selective and orally active SCoR2 (AKR1A1) inhibitor with an IC50 of 93 nM. JSD26 has 10-fold selectivity for SCoR2 versus AKR1B1. JSD26 can be used for the study acute kidney injury (AKI) [1].
Product Specifications
CAS Number
2353515-08-7
UNSPSC
12352005
Target
Aldose Reductase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Smiles
O=C1NC(C2(C3=C(C4=CC=C(C5CC5)C=C42)C=CC=C3)N1)=O
Molecular Formula
C18H14N2O2
Molecular Weight
290.32
References & Citations
[1]Zhou HL, et al. Identification of a Selective SCoR2 Inhibitor That Protects Against Acute Kidney Injury. J Med Chem. 2023 Apr 27;66 (8) :5657-5668.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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